Kluver-Bucy syndrome
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[[Category:Neuropsychological syndromes]] | [[Category:Neuropsychological syndromes]] | ||
| - | ''' | + | '''Klüver-Bucy syndrome''' is a neurobehavioral disorder that occurs when there is damage to the right and left medial temporal lobes in the brain. The syndrome is named for Heinrich Klüver and Paul Bucy, who attempted to determine its function by removing the temporal lobe bilaterally in rhesus monkeys. There was discovered different effects in monkeys and humans. |
== In Rhesus Monkeys == | == In Rhesus Monkeys == | ||
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Aside from accidental damage, extensive bilateral temporal damage can arise from herpes, encephalitis, cardiovascular disease, and dementias of degenerative ([[Alzheimer's Disease]]) or post-traumatic origins. In general, the syndrome rarely develops in humans. | Aside from accidental damage, extensive bilateral temporal damage can arise from herpes, encephalitis, cardiovascular disease, and dementias of degenerative ([[Alzheimer's Disease]]) or post-traumatic origins. In general, the syndrome rarely develops in humans. | ||
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| + | ==External links== | ||
| + | * [http://www.ninds.nih.gov/disorders/kluver_bucy/kluver_bucy.htm The National Institute of Neurological Disorders and Stroke - Kluver-Bucy Syndrome] | ||
| + | *[http://neuro.psychiatryonline.org/cgi/content/full/11/1/116 Anatomic Basis of Klüver-Bucy Syndrome] | ||
| + | *[http://cogprints.org/2872/ Monkeys With Amygdala Lesions] | ||
| + | *[http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2004;volume=52;issue=3;spage=369;epage=371;aulast=Jha Six distinct case studies of KBS in India] | ||
Revision as of 00:41, 24 April 2008
Klüver-Bucy syndrome is a neurobehavioral disorder that occurs when there is damage to the right and left medial temporal lobes in the brain. The syndrome is named for Heinrich Klüver and Paul Bucy, who attempted to determine its function by removing the temporal lobe bilaterally in rhesus monkeys. There was discovered different effects in monkeys and humans.
In Rhesus Monkeys
Symptoms
-Visual agnosia: Though the monkeys could see, they were unable to recognize even previously familiar objects, or their use
-Hypersexualism: Their overt sexual behavior increased dramatically and the monkeys indulged in indiscriminate sexual behavior including masturbation, heterosexual and homosexual acts.
-Oral tendencies: They would have a desire to explore everything examine their world with their mouths instead of their eyes
-Emotional changes: The monkeys became less expressive in their face and vocalizations. There is also a loss of normal fear and anger responses. For example, even after being attacked by a snake, the monkey would willingly approach it again; these changes are connected to any lesion of the amygdala.
In Humans
People with a bilateral lesion in their temporal lobes show similar behaviors to the monkeys such as an oral tendency to explore, hypersexuality, and flattened emotions. In addition, other behaviors may include tactile exploratory behavior (socially inappropriate touching), bulimia, memory disorders, visual agnosia or prosopagnosia.
Aside from accidental damage, extensive bilateral temporal damage can arise from herpes, encephalitis, cardiovascular disease, and dementias of degenerative (Alzheimer's Disease) or post-traumatic origins. In general, the syndrome rarely develops in humans.
