Nucleus basalis
From Psy3242
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| + | == Definition == | ||
| + | the gray matter of the substantia innominata of the forebrain that consists mostly of cholinergic neurons [http://medical.merriam-webster.com/medical/nucleus%20basalis] | ||
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| + | == Clinical significance == | ||
In Parkinson and Alzheimer diseases the nucleus undergoes degeneration. A decrease in acetylcholine production is seen in Alzheimer's disease, Lewy body dementia and some Parkinson Disease patients showing abnormal brain function, leading to a general decrease of mental capacity and learning. | In Parkinson and Alzheimer diseases the nucleus undergoes degeneration. A decrease in acetylcholine production is seen in Alzheimer's disease, Lewy body dementia and some Parkinson Disease patients showing abnormal brain function, leading to a general decrease of mental capacity and learning. | ||
Current revision as of 20:06, 27 April 2008
Definition
the gray matter of the substantia innominata of the forebrain that consists mostly of cholinergic neurons [1]
Clinical significance
In Parkinson and Alzheimer diseases the nucleus undergoes degeneration. A decrease in acetylcholine production is seen in Alzheimer's disease, Lewy body dementia and some Parkinson Disease patients showing abnormal brain function, leading to a general decrease of mental capacity and learning.
