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Welcome to the very first official newsletter
of the Wilfrid Derome Building (W.D.B.).
As some may know this was orignally called
the Temperance Brennan Forum. Thank you for
subscribing. We have over 100 members and the forum is now
over 1 year old. This newsletter will be published at the end of
every month.

Bone cartilege

...an article by Iain Barnwell As we grow older, our bones begin to harden.
This is known as ossification. A soft material called
hyaline cartilage forms the initial bone structure.
Then half way down the shaft (diaphysis) of long bone
cartilage, a calcified (formed by calcium) matrix
begins to appear surrounded by the uncalcified matrix.
This calcified matrix becomes the primary ossification centre.
Once ossified, the arteries and veins form inside a space
called the medullary cavity. These supply the bone with its
required nutrients and transport white blood cells that
originate in the bone marrow. At the epiphyses (the ends),
secondary ossification centres form in the uncalcified matrices.
The hyaline cartilage between the diaphysis and the epiphyses
becomes the epiphyseal plates at each end which allow for
bone extension throughout childhood and up to adulthood.
At the same time, the articular cartilage forms and acts as
a buffer for jointed bone movement.

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