Herpes simplex encephalitis

From Psy3242

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[[Category:Neuropsychological syndromes]]
[[Category:Neuropsychological syndromes]]
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== Summary ==
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'''Herpes Simplex Encephalitis (HSE)''' is caused by Herpes simplex virus type 1 (HSV-1). HSV-1 induces programmed cell death in neuronal cells but it is not clear if the HSE is triggered by the virus itself or the immune system’s response to the infection. In any case, HSE attacks the brain causing bilateral focal damage that is usually localized to the medial '''temporal lobes''', through sometimes spreading to the inferior temporal and frontal temporal areas also. HSE results in severe memory deficits and occasionally executive deficits as well. Because of the bilateral destruction of the medial temporal lobe global amnesia can be suffered by survivors.  '''Clive Wearing''', a famous case study, became '''left globally amnesic''' as a result of HSE.

Revision as of 20:08, 21 April 2008


Summary

Herpes Simplex Encephalitis (HSE) is caused by Herpes simplex virus type 1 (HSV-1). HSV-1 induces programmed cell death in neuronal cells but it is not clear if the HSE is triggered by the virus itself or the immune system’s response to the infection. In any case, HSE attacks the brain causing bilateral focal damage that is usually localized to the medial temporal lobes, through sometimes spreading to the inferior temporal and frontal temporal areas also. HSE results in severe memory deficits and occasionally executive deficits as well. Because of the bilateral destruction of the medial temporal lobe global amnesia can be suffered by survivors. Clive Wearing, a famous case study, became left globally amnesic as a result of HSE.

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