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| + | Lorem ipsum dolor sit amet, consectetur adipiscing elit. Pellentesque sed purus nisl. Mauris varius neque id arcu tempor porttitor. Nulla lacinia, eros non vestibulum dignissim, quam nunc ullamcorper dolor, nec egestas metus massa accumsan orci. In faucibus efficitur dolor vel porttitor. Donec lacinia sapien sed erat iaculis, eget mollis magna molestie. Quisque porta enim orci, eget euismod sem vulputate eu. Morbi eleifend mauris odio, congue egestas nulla semper id. Donec enim tellus, molestie vitae convallis non, dignissim at dui. Sed eget ante ut dui iaculis tempus eu et nisi. Nullam finibus erat quis mi egestas efficitur. |
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| - | The following popper user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlDisplay Settings:AbstractThe following popper user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlSend to:
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| - | Mol Microbiol. 1989 Aug;3(8):995-1002.
| + | |
| - | The terminus of the Escherichia coli chromosome is flanked by several polar replication pause sites.
| + | |
| - | François V, Louarn J, Louarn JM.
| + | |
| - | Source
| + | |
| - | Centre de Biochimie et de Génétique Cellulaires du CNRS, Toulouse, France.
| + | |
| - | Abstract
| + | |
| - | Replication of two small 'constrained' regions of the Escherichia coli chromosome, one bordered by replication terminator T1 and the other by T2, displays normal velocity in the normal direction whereas it is much slower in the opposite direction (de Massy et al., 1987). The presence of multiple polar terminators has been investigated, using a bacteriophage lambda derivative which provides a replication origin movable to predetermined loci and inducible on demand. The amount of DNA made from this induced origin was determined by in vivo labelling and hybridization to probes of the surrounding region. A redundancy of terminator-like sequences, or pause sites, has been disclosed. So far, two polar pause sites, in the same orientation and separated by 50 or 80 kb, have been localized on each side of the terminus region. The results are discussed in relation to previously observations indicating that these regions are refractory to genomic inversions.
| + | |
| - | PMID: 2532703 [PubMed - indexed for MEDLINE]
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| - | The following toggler user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface control
| + | |
| - | MeSH Terms, Substances
| + | |
| - | MeSH Terms
| + | |
| - | Bacteriophage lambda/genetics
| + | |
| - | Base Sequence
| + | |
| - | Chromosome Mapping
| + | |
| - | Chromosomes, Bacterial/metabolism*
| + | |
| - | DNA Replication*
| + | |
| - | Escherichia coli/genetics*
| + | |
| - | Immunoblotting
| + | |
| - | Sequence Homology, Nucleic Acid
| + | |
| - | Terminator Regions, Genetic
| + | |
| - | Thymidine/metabolism
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| - | Time Factors
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| - | Substances
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| - | Thymidine
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| + | Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nulla hendrerit auctor purus, eget mollis lorem fringilla sed. Nunc sodales ullamcorper lorem eget commodo. Pellentesque velit metus, mollis et ex id, interdum tempor nibh. Vivamus eget metus sem. Duis consectetur arcu non risus tempus fringilla. Duis fermentum diam a enim vestibulum posuere. Nullam tempus laoreet molestie. |
| - | The following setswitch user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlAdd to Favorites
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| - | Related citations in PubMed
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| - | Constraints in chromosomal inversions in Escherichia coli are not explained by replication pausing at inverted terminator-like sequences.
| + | |
| - | [Mol Microbiol. 1990]
| + | |
| - | The terminus region of the Escherichia coli chromosome contains two separate loci that exhibit polar inhibition of replication.
| + | |
| - | [Proc Natl Acad Sci U S A. 1987]
| + | |
| - | Inhibition of replication forks exiting the terminus region of the Escherichia coli chromosome occurs at two loci separated by 5 min.
| + | |
| - | [Proc Natl Acad Sci U S A. 1987]
| + | |
| - | Review Termination of DNA replication of bacterial and plasmid chromosomes.
| + | |
| - | [Mol Microbiol. 1999]
| + | |
| - | Review Mechanisms of polar arrest of a replication fork.
| + | |
| - | [Mol Microbiol. 2009]
| + | |
| - | See reviews...
| + | |
| - | See all...
| + | |
| - | Cited by 10 PubMed Central articles
| + | |
| - | Review Replication termination in Escherichia coli: structure and antihelicase activity of the Tus-Ter complex.
| + | |
| - | [Microbiol Mol Biol Rev. 2005]
| + | |
| - | Review Linkage map of Escherichia coli K-12, edition 10: the traditional map.
| + | |
| - | [Microbiol Mol Biol Rev. 1998]
| + | |
| - | Search for additional replication terminators in the Bacillus subtilis 168 chromosome.
| + | |
| - | [J Bacteriol. 1997]
| + | |
| - | See all...
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| - | Related information
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| - | Related Citations
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| - | Compound
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| - | The terminus of the Escherichia coli chromosome is flanked by several polar repl...
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| - | The following popper user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlDisplay Settings:AbstractThe following popper user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlSend to:
| + | |
| - | Mol Microbiol. 1989 Aug;3(8):995-1002.
| + | |
| - | The terminus of the Escherichia coli chromosome is flanked by several polar replication pause sites.
| + | |
| - | François V, Louarn J, Louarn JM.
| + | |
| - | Source
| + | |
| - | Centre de Biochimie et de Génétique Cellulaires du CNRS, Toulouse, France.
| + | |
| - | Abstract
| + | |
| - | Replication of two small 'constrained' regions of the Escherichia coli chromosome, one bordered by replication terminator T1 and the other by T2, displays normal velocity in the normal direction whereas it is much slower in the opposite direction (de Massy et al., 1987). The presence of multiple polar terminators has been investigated, using a bacteriophage lambda derivative which provides a replication origin movable to predetermined loci and inducible on demand. The amount of DNA made from this induced origin was determined by in vivo labelling and hybridization to probes of the surrounding region. A redundancy of terminator-like sequences, or pause sites, has been disclosed. So far, two polar pause sites, in the same orientation and separated by 50 or 80 kb, have been localized on each side of the terminus region. The results are discussed in relation to previously observations indicating that these regions are refractory to genomic inversions.
| + | |
| - | PMID: 2532703 [PubMed - indexed for MEDLINE]
| + | |
| - | The following toggler user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface control
| + | |
| - | MeSH Terms, Substances
| + | |
| - | MeSH Terms
| + | |
| - | Bacteriophage lambda/genetics
| + | |
| - | Base Sequence
| + | |
| - | Chromosome Mapping
| + | |
| - | Chromosomes, Bacterial/metabolism*
| + | |
| - | DNA Replication*
| + | |
| - | Escherichia coli/genetics*
| + | |
| - | Immunoblotting
| + | |
| - | Sequence Homology, Nucleic Acid
| + | |
| - | Terminator Regions, Genetic
| + | |
| - | Thymidine/metabolism
| + | |
| - | Time Factors
| + | |
| - | Substances
| + | |
| - | Thymidine
| + | |
| - | The following toggler user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface control
| + | |
| - | LinkOut - more resources
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| - | Supplemental Content
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| | | | |
| - | Save items
| + | Etiam placerat augue quis justo lobortis, at pellentesque ligula consectetur. Nam scelerisque a erat ac mollis. Nulla egestas est non arcu tincidunt, quis mattis mauris lacinia. Quisque finibus purus lacinia interdum interdum. Proin quis viverra magna, et rhoncus felis. Nam eget leo vel mauris venenatis tincidunt ut vel quam. Nunc sodales venenatis dui, sit amet elementum arcu hendrerit at. |
| - | The following setswitch user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlAdd to Favorites
| + | |
| - | View more options
| + | |
| - | Related citations in PubMed
| + | |
| - | Constraints in chromosomal inversions in Escherichia coli are not explained by replication pausing at inverted terminator-like sequences.
| + | |
| - | [Mol Microbiol. 1990]
| + | |
| - | The terminus region of the Escherichia coli chromosome contains two separate loci that exhibit polar inhibition of replication.
| + | |
| - | [Proc Natl Acad Sci U S A. 1987]
| + | |
| - | Inhibition of replication forks exiting the terminus region of the Escherichia coli chromosome occurs at two loci separated by 5 min.
| + | |
| - | [Proc Natl Acad Sci U S A. 1987]
| + | |
| - | Review Termination of DNA replication of bacterial and plasmid chromosomes.
| + | |
| - | [Mol Microbiol. 1999]
| + | |
| - | Review Mechanisms of polar arrest of a replication fork.
| + | |
| - | [Mol Microbiol. 2009]
| + | |
| - | See reviews...
| + | |
| - | See all...
| + | |
| - | Cited by 10 PubMed Central articles
| + | |
| - | Review Replication termination in Escherichia coli: structure and antihelicase activity of the Tus-Ter complex.
| + | |
| - | [Microbiol Mol Biol Rev. 2005]
| + | |
| - | Review Linkage map of Escherichia coli K-12, edition 10: the traditional map.
| + | |
| - | [Microbiol Mol Biol Rev. 1998]
| + | |
| - | Search for additional replication terminators in the Bacillus subtilis 168 chromosome.
| + | |
| - | [J Bacteriol. 1997]
| + | |
| - | See all...
| + | |
| - | Related information
| + | |
| - | Related Citations
| + | |
| - | Compound
| + | |
| - | Compound (MeSH Keyword)
| + | |
| - | Substance
| + | |
| - | Substance (MeSH Keyword)
| + | |
| - | Cited in PMC
| + | |
| - | Recent activity
| + | |
| - | Clear Turn Off
| + | |
| - | The terminus of the Escherichia coli chromosome is flanked by several polar repl...
| + | |
| - | PubMed
| + | |
| - | See more...
| + | |
| - | You are here: NCBI > Literature > PubMedWrite to the Help Desk
| + | |
| - | Simple NCBI Directory
| + | |
| - | GETTING STARTED
| + | |
| - | NCBI Education
| + | |
| - | NCBI Help Manual
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| + | |
| - | Training & Tutorials
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| - | Genes & Expression
| + | |
| - | Genetics & Medicine
| + | |
| - | Genomes & Maps
| + | |
| - | Homology
| + | |
| - | Literature
| + | |
| - | Proteins
| + | |
| - | Sequence Analysis
| + | |
| - | Taxonomy
| + | |
| - | Training & Tutorials
| + | |
| - | Variation
| + | |
| - | POPULAR
| + | |
| - | PubMed
| + | |
| - | Nucleotide
| + | |
| - | BLAST
| + | |
| - | PubMed Central
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| - | Gene
| + | |
| - | Bookshelf
| + | |
| - | Protein
| + | |
| - | OMIM
| + | |
| - | Genome
| + | |
| - | SNP
| + | |
| - | Structure
| + | |
| - | FEATURED
| + | |
| - | Genetic Testing Registry
| + | |
| - | PubMed Health
| + | |
| - | GenBank
| + | |
| - | Reference Sequences
| + | |
| - | Map Viewer
| + | |
| - | Human Genome
| + | |
| - | Mouse Genome
| + | |
| - | Influenza Virus
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| - | Primer-BLAST
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| - | Sequence Read Archive
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Lorem ipsum dolor sit amet, consectetur adipiscing elit. Pellentesque sed purus nisl. Mauris varius neque id arcu tempor porttitor. Nulla lacinia, eros non vestibulum dignissim, quam nunc ullamcorper dolor, nec egestas metus massa accumsan orci. In faucibus efficitur dolor vel porttitor. Donec lacinia sapien sed erat iaculis, eget mollis magna molestie. Quisque porta enim orci, eget euismod sem vulputate eu. Morbi eleifend mauris odio, congue egestas nulla semper id. Donec enim tellus, molestie vitae convallis non, dignissim at dui. Sed eget ante ut dui iaculis tempus eu et nisi. Nullam finibus erat quis mi egestas efficitur.
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Etiam placerat augue quis justo lobortis, at pellentesque ligula consectetur. Nam scelerisque a erat ac mollis. Nulla egestas est non arcu tincidunt, quis mattis mauris lacinia. Quisque finibus purus lacinia interdum interdum. Proin quis viverra magna, et rhoncus felis. Nam eget leo vel mauris venenatis tincidunt ut vel quam. Nunc sodales venenatis dui, sit amet elementum arcu hendrerit at.
